Alzheimer's disease is feared by nearly everyone, especially as they grow older. It is estimated that about three million Americans have Alzheimer's, and the number is growing rapidly. What brings on Alzheimer's is not completely known. But research has shed some light on one possible cause for this devastating disease.
Researchers have found links between Alzheimer's and high cholesterol. The cholesterol that builds plaque in arteries has also been found in brain cells (neurons).
How Cholesterol Damages the Brain
In Alzheimer's disease, there is a buildup of masses of protein in the brain known as senile plaque. These plaques bind to neurons and eventually kill them. The loss of these neurons is what results in diminished memory and loss of cognitive functions. Damage cannot be undone, but future damage can be slowed.
The Good News
Lowering cholesterol reduces the plaque in arteries and brain cells. The studies show that when cholesterol levels are in the normal range, plaque does not build up in the brain.
What You Can Do Now
If you know you have high cholesterol, suspect you might have high cholesterol, or just don't know – see your doctor now and have your cholesterol level tested. There are several types of cholesterol – both good and bad. LDL cholesterol is the main culprit in causing plaque build-up and artery and brain damage. Healthy lifestyle changes, such as reducing saturated fat, losing weight, and increasing physical activity will lower cholesterol levels for most people. If those approaches don't lower cholesterol enough, drugs called statins can dramatically lower cholesterol. These drugs are available only by prescription and are sold under brand names such as Lipitor®, Zocor®, Mevacor®, Pravachol®, and Crestor®.
Research Results
In a University of California study of more than 1,000 elderly women, those who were given cholesterol-lowering medications had less mental impairment than those who did not use the drugs. Over the four-year course of the study, women who were able to lower LDL cholesterol levels were about 50 percent less likely to have cognitive impairment than were those whose LDL cholesterol levels increased.
Take Action!
You already know that keeping LDL and overall cholesterol levels low can protect you from heart disease and stroke. These studies show that managing cholesterol levels could also be an important factor in lowering your risk of Alzheimer's and other cognitive problems. See your doctor to find out if you need to lower your cholesterol and, if so, what you will need to do. |
